CLARITHROMYCINE 250 mg Film-coated tablet

In all cases, you must strictly comply with your doctor’s prescription.

Dosage:

Adult with normal renal and hepatic function:

• Pharyngitis, tonsillitis, mouth infections, uncomplicated skin infections: 1 tablet twice a day.
• Acute maxillary sinusitis, bacterial exacerbation of chronic bronchitis, pneumonia: 2 tablets twice a day.
• Eradication of Helicobacter pylori in peptic ulceration:
• clarithromycin 500 mg combined with omeprazole 20 mg and amoxicillin 1000 mg, all twice a day for 7 days;
• Other triple therapy: clarithromycin 500 mg combined with lansoprazole 30 mg and amoxicillin 1000 mg, all twice a day for 7 days;

(Amoxicillin can be replaced with metronidazole 500 mg or tinidazole 500 mg). To ensure healing, it is recommended to further the triple treatment with omeprazole or lansoprazole for up to 3 weeks for patients with active duodenal ulcer, and for up to 3 to 5 weeks for patients with active gastric ulcer:

• Omeprazole 20 mg per day, if the treatment is started by omeprazole.
• Or lansoprazole 30 mg per day, if the treatment is started by lansoprazole.
• Mycobacterial infections due to M. avium in patients with HIV (+):
• Patients weighing over 50 kg: 2000 mg/day, divided into 2 doses per day.
• Patients weighing under or equal to 50 kg: 1500 mg/day, divided into 2 doses per day.

Adult with renal insufficiency (creatinine clearance < 30 ml/mn):

• The dose should be reduced by half (250 mg of clarithromycin once a day or 250 mg of clarithromycin twice a day in more severe infections). For infections due to M. avium: 1000 mg/day.

Mode of administration: Oral route.

STORAGE: Store below 30ºC. Protect from light, heat and humidity.